General meaning of a route
A route is defined as a journey with a beginning and an end. The beginning and the end can be at the same location or at different locations. Along the route, places or points of interest can be mentioned
Specific meaning of a route
The concept of a route is frequently used in comparison with the concept of a track.
A route fits on a network and "knows" when you reach a crossroad or a division. GPS devices supporting 'routes' provide turn by turn instruction (=turn left, turn right,…). It frequently also provides a reference to other objects in the network (e.g. turn from street X into street Y, passing object A).